　　The boisterous, arrogant professor Challenger, a reputed biologist and anthropologist, dares the London Zoological Society to mount an expedition to verify his spectacular claim, without physical proof, that his previous expedition to the Amazonian basin found live dinosaurs. Apart from him and his 'socialite' counterpart, professor Summerlee, it consists of experienced discoverer Lord Roxbury, the young reporter Ed Malone -who got publicly struck down with Challenger's umbrella at his arrival- and Jennifer Holmes, Malone's news agency's boss's daughter, essentially as conditions for putting up the money. In Brazil they are joined by Jennifer's brother David and local 'guide' Manuel Gomez. They soon discover the dinosaurs are real and dangerous, like giant spiders, but loose their helicopter and thus are desperate for a way down from the isolated plateau. They learn Roxbury knew about the fate of Burton White, an explorer whose diary they find, thus presume to be dead, in search of diamonds, and confirmation of the local tribe being the lethal guardians of the plateau's secrets, but also get surprising help...

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　　32歲的勞倫·柯倫（克里斯蒂娜·里奇）和丈夫羅素（布萊登·佛雷切）搬進了設(shè)備先進齊全的新公寓。剛剛因為失去孩子而遭受了心理創(chuàng)傷患躁郁癥的勞倫對公寓的安保監(jiān)控系統(tǒng)很滿意，但隨后發(fā)現(xiàn)公寓里有些不對勁，她懷疑酒店的擁有者暗中非法操控住在其中的用戶，但她的丈夫認(rèn)為這些都是她的想象。勞倫獨自開始調(diào)查建造公寓的公司，并雇傭了一個幫手-陰謀論者弗儂·沙斯菲爾德（約翰·庫薩克）。弗儂認(rèn)為這間公寓是個試驗場所，里面的住戶是個巨大洗腦陰謀的小白鼠。隨著調(diào)查深入，勞倫也遇到了生命威脅……

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